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  Vol. 1 No. 1, September 1992 TABLE OF CONTENTS
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Human Gene Therapy: A Role for the Primary Care Physician

Cynthia J. Schmeichel, PhD; Jerod M. Loeb, PhD

Arch Fam Med. 1992;1(1):113-120.

Article references have been provided for searching and linking. Additional reference information may be available in the article PDF.

1. Anderson WF. Human gene therapy. Science. 1992;256:808-813. FREE FULL TEXT
2. Human gene therapy. Presented at the conference of the National Institutes of Health and National Heart, Lung, and Blood Institute; Bethesda, Md; December 4-6, 1991.
3. Cornetta K, Morgan RA, Anderson FW. Safety issues related to retroviral-mediated gene transfer in humans: review. Hum Gene Ther. 1991;2:5-14. PUBMED
4. Ledley FD. Clinical considerations in the design of protocols for somatic gene therapy. Hum Gene Ther. 1991;2:77-83. PUBMED
5. Ledley FD, Woo SLC, Ferry GD, et al. Hepatocellular transplantation in acute hepatic failure and targeting genetic markers to hepatic cells: clinical protocol. Hum Gene Ther. 1991;2:331-358. PUBMED
6. Fleischman RA. Southwestern internal medicine conference: human gene therapy. Am J Med Sci. 1991;301:353-363. PUBMED
7. Kelley W. Gene therapy in humans: a new era begins. Ann Intern Med. 1991;114:697-698. FREE FULL TEXT
8. McGarrity GJ. The metamorphosis of gene insertion and gene therapy. Hum Gene Ther. 1991;2:3-4. PUBMED
9. Proposed amendment to appendix D. In: Recombinant DNA Technical Bulletin. Bethesda, Md: US Dept of Health and Human Services, Public Health Service, National Institutes of Health; 1992: 29-36.
10. Friedmann T. The evolving concept of gene therapy. Hum Gene Ther. 1990;1:175-181. PUBMED
11. Center for Biologics Evaluation and Research, US Food and Drug Administration. Points to consider in human somatic cell therapy and gene therapy. Hum Gene Ther. 1991;2:251-256. PUBMED
12. Dick JE, Kamel-Reid S, Murdock B, Doedens M. Gene transfer into normal human hematopoietic cells using in vitro and in vivo assays. Blood. 1991;78:624-634. FREE FULL TEXT
13. Merz B. Researchers find stem cell: clinical possibilities touted. Am Med News. November 1991:2, 34.
14. Anderson RW, Blaese RM, Culver K. The ADA human gene therapy clinical protocol. Hum Gene Ther. 1990;1:331-362. PUBMED
15. Rosenberg SA, Kasid A, Anderson WF, et al. TNR/TIL human gene therapy clinical protocol. Hum Gene Ther. 1990;1:443-462.
16. Rosenberg SA, Blaese RM, Anderson WF. The N2-TIL human gene transfer clinical protocol. Hum Gene Ther. 1990;1:73-92. PUBMED
17. Culver K, Cornetta K, Morgan R, et al. Lymphocytes as cellular vehicles for gene therapy in mouse and man. Proc Natl Acad Sci USA. 1991;88:3155-3159. FREE FULL TEXT
18. Brenner M, Mirro J, Hurwitz C, et al. Autologous bone marrow transplant for children with AML in first complete remission: use of marker genes to investigate the biology of marrow reconstitution and the mechanism of relapse. Hum Gene Ther. 1991;2:137-159. PUBMED
19. Baum CM, Weissman IL, Tsukamoto AS, Bucvkle AM, Peault B. Isolation of a candidate human hematopoietic stem-cell population. Proc Natl Acad Sci USA. 1992;89:2804-2808. FREE FULL TEXT
20. Lynch CM, Clowes MM, Osborne WRA, Clowes AW, Miller DA. Long-term expression of human adenosine deaminase in vascular smooth muscle cells of rats: a model for gene therapy. Proc Natl Acad Sci USA. 1992;89:1138-1142. FREE FULL TEXT
21. Rosenfeld MA, Siegried W, Yoshimura K, et al. Adenovirus-mediated transfer of a recombinant alpha1-anti-trypsin gene to the lung epithelium in vivo. Science. 1991;252:431-434. FREE FULL TEXT
22. Palella TD, Hidaka Y, Silverman W, Levine M, Glorioso J, Kelley WN. Expression of human HPRT mRNA in brains of mice infected with a recombinant herpes simplex virus-1 vector. Gene. 1989;80:137-144. PUBMED
23. Friedman R. Gene delivery without retrovirus. BioWorld Today. 1991;2:3.
24. Payne S, Potter R. DNA seen as drug in gene injection trial. BioWorld Today. 1992;3(115):1, 3.
25. Dhawan J, Pan LC, Pavlath GK, Travis MA, Lanctot AM. Systemic delivery of human growth hormone by injection of genetically engineered myoblasts. Science. 1991;254:1509-1512. FREE FULL TEXT
26. Culver KW, Anderson WF, Blaese RM. Lymphocyte gene therapy. Hum Gene Ther. 1991;2:107-109. PUBMED
27. Anderson WF. End-of-the-year potpourri. Hum Gene Ther. 1992;2:229-300.
28. Rosenberg SA. Immunotherapy and gene therapy of cancer. Cancer Res. 1991;51(suppl): 5074s-5079s. FREE FULL TEXT
29. Rosenberg SA. Immunization of cancer patients using autologous cancer cells modified by insertion of the gene for tumor necrosis factor. Hum Gene Ther. 1992;3:57-74. PUBMED
30. Rosenberg SA. Immunization of cancer patients using autologous cancer cells modified by insertion of the gene for interleukin-2. Hum Gene Ther. 1992;3:75-93. PUBMED
31. Colombo MP, Ferrari G, Stoppacciaro A, et al. Granulocyte colony-stimulating factor gene transfer suppresses tumorigenicity of a murine adenocarcinoma in vivo. J Exp Med. 1991;173:889-897. FREE FULL TEXT
32. Gansbacher B, Zier K, Daniels B, Cronin K, Bannerji R, Gilboa E. Interleukin 2 gene transfer into tumor cells abrogates tumorigenicity and induces protective immunity. J Exp Med. 1990;172:1217-1224. FREE FULL TEXT
33. Gansbacher B, Bannerji R, Daniels B, Zier K, Cronin K, Gilboa E. Retroviral vector-mediated gamma interferon gene transfer into tumor cells generates potent and long lasting anti-tumor immunity. Cancer Res. 1990;50:7820-7825. FREE FULL TEXT
34. Barth RJ, Mule JJ, Spiess PJ, Rosenberg SA. Interferon gamma and tumor necrosis factor have a role in tumor regressions mediated by murine CD8 tumor-infiltrating lymphocytes. J Exp Med. 1991;173:647-658. FREE FULL TEXT
35. Golumbek PT, Lazenby AJ, Levitsky HI, et al. Treatment of established renal cancer by tumor cells engineered to secrete interleukin-4. Science. 1991;254:713-716. FREE FULL TEXT
36. Moolten FL, Wells JM, Heyman RA, Evans RM. Lymphoma regression induced by gancyclovir in mice bearing a herpes thymidine kinase transgene. Hum Gene Ther. 1990;1:125-134. PUBMED
37. Mullen CA, Kilstrup M, Blaese RM. Transfer of the bacterial gene for cytosine deaminase to mammalian cells confers lethal sensitivity to 5-fluorocytosine: a negative selection system. Proc Natl Acad Sci USA. 1992;89:33-37. FREE FULL TEXT
38. Bernstein K. Gene therapy trials for HIV patients. BioWorld Today. 1992;3(32):1. PUBMED
39. Nabel EG, Plautz G, Nabel GJ. Site-specific gene expression in vivo by direct gene transfer into the arterial wall. Science. 1990;249:1285-1288. FREE FULL TEXT
40. Kolberg R. Animal models point the way to human clinical trials. Science. 1992;256:772-773. FREE FULL TEXT