False-Positive and Indeterminate Human Immunodeficiency Virus Test Results in Pregnant Women
Terence I. Doran, MD, PhD;
Ernesto Parra, MD, MPH
Arch Fam Med. 2000;9:924-929.
Guidelines from the Centers for Disease Control and Prevention, Atlanta, Ga, recommend that all pregnant women be offered human immunodeficiency virus (HIV) testing to ensure that they have the opportunity to use currently available therapeutic interventions to reduce the risk infecting their offspring with HIV. These recommendations have resulted in an increased number of low-risk women being tested and a significant rise in the percentage of false-positive results from HIV antibody screening tests and ambiguous (indeterminate) findings from confirmatory tests. Women receiving such results are generally in emotional turmoil yet must make treatment choices if they prove to be infected. This article provides guidelines to help general medical practitioners to understand the nature of HIV testing, to assess a woman's infection status when initial tests are ambiguous, and to determine when treatment is appropriate.
From the Departments of Pediatrics (Dr Doran), and Family Practice (Dr Parra), University of Texas Health Science Center at San Antonio.
The Archives of Family Medicine Continuing Medical Education Program
Arch Fam Med. 2000;9(9):887-891.
THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES
Performance of an automated human immunodeficiency virus (HIV) antigen/antibody combined assay for prenatal screening for HIV infection in pregnant women
Garcia et al.
J Med Microbiol 2009;58:1529-1530.
Opportunities to Prevent HIV Transmission to Newborns
Goldschmidt and Fogler
Prenatal Screening for HIV: A Review of the Evidence for the U.S. Preventive Services Task Force
Chou et al.
ANN INTERN MED 2005;143:38-54.
| FULL TEXT