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Developmental Pharmacogenetics in Pediatric Rheumatology: Utilizing a New Paradigm to Effectively Treat Patients with Juvenile Idiopathic Arthritis with Methotrexate

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Figure 1
Figure 1

Comparison of MTXglun subgroups between oral (PO) and subcutaneous (SC) routes of administration. (a) Short chain polyglutamates (MTXglu1+2) were more predominant with PO administration, and (b) higher concentrations of long chain polyglutamates (MTXglu3−5) were more predominant with SC administration. Box and whisker plots are superimposed on data from individual patients. Boxes include the median and interquartile range, and whiskers indicate the 10th and 90th percentiles.

This Article

  1. Hum Genomics Proteomics vol. 2 no. 1