- Institution: Stanford Univ Med Ctr Lane Med Lib/Periodical Dept/Rm L109
- Sign In as Member / Individual
The Path Well Traveled: Using Mammalian Retroviruses to Guide Research on XMRV
Table 1
In Vitro Inhibitory Activities of FDA-Approved Antiretroviral Drugs Targeting HIV-1
| Virus | |||||
|---|---|---|---|---|---|
| Class of Antiviral | Drug Name (Abbreviation) | HIV-1 | HTLV-1 | Moloney MLV | XMRV |
| Nucleoside RT Inhibitors | Zidovudine (AZT) | Yes | Yes | Yes | Yes |
| Emtricitabine (FTC) | Yes | Yes | ND | ND | |
| Lamivudine (3TC) | Yes | Yes | No | No | |
| Didanosine (ddI) | Yes | Yes | Yes | ND | |
| Stavudine (d4T) | Yes | Yes | No | No | |
| Tenofovir (TDF) | Yes | Yes | No | No | |
| Nonnucleoside RT Inhibitors | Nevirapine (NVP) | Yes | ND | ND | No |
| Efavirenz (EFV) | Yes | ND | ND | No | |
| Protease Inhibitors | Ritonavir (RTV) | Yes | No | ND | No |
| Saquinovir (SQU) | Yes | No | ND | No | |
| Indinavir (IDV) | Yes | No | Yes | No | |
| Integrase Inhibitors | Raltegravir | Yes | ND | ND | ND |
| Entry/Fusion Inhibitors | Enfuvirtide (T20) | Yes | ND | ND | ND |
| Maraviroc | Yes | ND | ND | ND | |
