Finding Homes for Orphan Cytochrome P450s: CYP4V2 and CYP4F22 in Disease States
Figure 2
Polymorphisms in CYP4-encoding genes that are associated with disease
A. BCD-related mutations in CYP4V2 are compiled from ten separate studies; all eleven exons have been found to contain at least one mutation. B. In lamellar ichthyosis (type 3), seven different mutations have been linked to disease (7), with each affected individual homozygous for a single mutation.
