- Institution: Stanford Univ Med Ctr Lane Med Lib/Periodical Dept/Rm L109
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REELIN and Schizophrenia:
Table 2.
Increase in RELN mRNA after Treatment with Inhibitors of Histone Deacetyase
| AzadC | Fold increase |
|---|---|
| 1 μM | 19.7 ± 2.8 |
| 5 μM | 22.4 ± 2.9 |
| 10 μM | 18.5 ± 2.8 |
| Trichostatin A | Fold increase |
|---|---|
| NT2 neural progenitor cultures were treated with the indicated concentrations of drugs for 24 hr and RNA was isolated. The amount of RELN mRNA was quantified using competitive RT-PCR (4) and is expressed relative to control. | |
| 0.2 μM | 18.4 ± 2.0 |
| 1.0 μM | 21.1 ± 2.4 |
