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Non-nuclear Actions of Estrogen: New Targets for Prevention and Treatment of Cardiovascular Disease
Figure 1.
Functional regions of the human estrogen receptor α (ERα). These domains include a ligand-independent transactivation function domain (AF-1), DNA-binding domain, hormone-binding domain and ligand-dependent transactivation function domain (AF-2). Putative regions of interaction with other proteins and sites of phosphorylation by various kinases are also shown.
