Allosteric Modulators: The New Generation of Receptor Antagonist

  Figure 7.
Figure 7.

Receptor functionality vs receptor binding. The non-competitive antagonist clopropan[b]chromen-1a-carboxylic acid ester inhibits the function of a glutamate receptor without appreciably affecting glutamate binding. Data redrawn from (34).

This Article

  1. MI August 2004 vol. 4 no. 4 222-229