Allosteric Modulators: The New Generation of Receptor Antagonist

Table 2.

Unique Features of Allosteric Ligands

  • Have texture in antagonism

  • Produce probe dependent

  • Produce effects through protein (have separate binding sites)

  • Produce saturable antagonism (dissociate magnitude from duration)

  • Can preserve physiological

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  1. MI August 2004 vol. 4 no. 4 222-229
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