CANCER STEM CELLS: Redefining the Paradigm of Cancer Treatment Strategies

Table 1.

Routes to Stem Cell Activation

Activation Mechanism Target Cell/Organ Cancer
Examples are provided of stem cell activation by different mechanisms. For each type there are several known examples, but only a single example is shown.
None Naturally activated stem cell Retinoblast Retinoblastoma
Inflammation Activates cell growth Colon Colon cancer
Viral infection Stimulates immune response Liver Hepatocellular carcinoma
Hormones Stimulates cell growth Breast Breast cancer
Bacterial infection Inflammation Stomach Gastric cancer
Tumor suppressor Stem cell proliferation Colon Colon cancer
Irritants Inflammation Lung Lung cancer

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  1. MI June 2006 vol. 6 no. 3 140-148
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