Shell Shock: An Old Injury with New Weapons

Table 2.

Co-treatment of TBI and Post-Traumatic Stress Disorder

Treatment Examples Rationale
SSRI antidepressants (2, 18, 26) Sertraline, paroxetine, fluoxetine, citalopram, fluvoxamine Considered first-line therapy for both PTSD and depression
Other antidepressants (18) Bupropion, nefazodone, trazodone, venlafaxine, phenelzine Considered second-line therapy for PTSD and depression
Sympatholytics (18) Prazocin Block autonomic hyperarousal, treat nightmares
Other psychotropic drugs (18) Carbamazepine, duloxetine For irritability, flash anger, and violent outbursts
Anticonvulsants (2) Valproate migraines and behavioral symptoms
Atypical antipsychotics (18) Quetiapine For insomnia
Stimulants (2) Methylphenidate, dextroamphetamine for attention problems or information processing

This Article

  1. MI October 2008 vol. 8 no. 5 204-218