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ORIGINAL ARTICLE
Year : 2013  |  Volume : 1  |  Issue : 2  |  Page : 54-57

Asymptomatic bacteriuria in HIV positive individuals in a tertiary care hospital


Department of Microbiology, Bangalore Medical College and Research Institute, Bangalore, Karnataka, India

Correspondence Address:
Asima Banu
34/1 Sree Ram Mandir Road, Basavangudi, Bangalore 560 004, Karnataka
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/2321-9157 .126630

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Aims: To determine the prevalence, bacterial profile and antimicrobial susceptibility of asymptomatic bacteriuria in Human Immunodeficiency Virus (HIV) positive individuals. Materials and Methods: Urine from 300 HIV positive individuals were collected and cultured on cysteine lactose electrolyte deficient (CLED) agar and identified using standard techniques. Modified Kirby Bauer disc diffusion test was done according to Central Laboratory Standards Institute (CLSI) guidelines for antimicrobial sensitivity testing of the isolates. Results were compiled and statistically analyzed. Results: Of the 300 patients, 211 (70.3%) showed no growth, 77 (25.7%) had insignificant bacteriuria with a colony count of <10 5 CFU/ml and 12 (4.0%) had significant bacteriuria with colony count >10 5 CFU/ml without any signs or symptoms of urinary tract infections. The bacteriuria was significantly more in females (83.3%) than males (16.7%) with a P value of < 0.001. Eight (66.7%) cases of significant bacteriuria occurred in patients who were not on cotrimoxazole prophylaxis whereas 4 (33.3%) cases occurred in those who were on cotrimoxazole prophylaxis for at least one year. Conclusion: The incidence of asymptomatic bacteriuria was relatively less as compared to other studies and no correlation was found with CD4 counts, although evaluation with a larger study population needs to be undertaken.


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