IBMS BoneKEy | Perspective

Effects of inflammatory bowel diseases on bone metabolism

Francisco A Sylvester

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DOI:10.1138/20090407

Abstract

Inflammatory bowel diseases (IBDs) are chronic inflammatory conditions that involve the gastrointestinal tract and affect approximately 1.2 million Americans, of whom 25% are diagnosed as children. The incidence of IBD is increasing worldwide. The term IBD encompasses two distinct entities, Crohn's disease and ulcerative colitis. Both diseases are frequently associated with decreased bone mineral mass. This Perspective examines the prevalence, mechanisms and optimization of bone health in adults and children with IBD.

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