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  Vol. 6 No. 2, March 1997 TABLE OF CONTENTS
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Compliance With Influenza Vaccination

Its Relation With Epidemiologic and Sociopsychological Factors

Gerrit A. van Essen, MD, PhD; Maria M. Kuyvenhoven, PhD; Ruut A. de Melker, MD, PhD

Arch Fam Med. 1997;6(2):157-162.


Abstract

Objective
To identify patient characteristics that are associated with compliance with influenza vaccination reminders in high-risk patients.

Design
Registration of the vaccination of high-risk patients invited by their family physicians. Factors that might be associated with compliance were evaluated, eg, sex, age, insurance, diagnosis, seriousness, and multiple indications. A questionnaire about sociopsychological factors was sent to all noncompliant patients and a random sample of 25% of compliant patients.

Setting
Four single and 3 partnership practices with 2142 high-risk patients in a total of 26 000 patients in the Netherlands.

Main Outcome Measures
(1) Compliance by atrisk group; odds ratios (ORs) for epidemiologic and diagnosis-based factors, adjusted by multiple logistic regression analysis; (2) adjusted ORs (adj ORs) for sociopsychological factors; and (3) decisive reason whether to comply.

Results
Compliance was 86% (95% confidence interval [CI], 85%-88%), with little difference between at-risk groups. The epidemiologic factors age older than 50 years (adj OR, 1.9; 95% CI, 1.5-2.5) and multiple indication (adj OR, 2.2; 95% CI, 1.3-3.6) were related to compliance, independent of at-risk group. Belief in the absence of side effects (adj OR, 10.5; 95% CI, 5.5-20.2) and in the efficacy of the vaccine (adj OR, 5.6; 95% CI, 3.0-10.2) were most positively associated with compliance. Perceived susceptibility to influenza also was associated (adj OR, 2.9; 95% CI, 1.5-5.8), but perception of one's health was not. There was a negative association of compliance in the interaction of age younger than 50 years and disbelief in the possible complications of influenza (adj OR, 0.2; 95% CI, 0.0-0.5). These factors and the family physician's invitation were decisive.

Conclusions
Information about the protection and the side effects of vaccination and the complications of influenza should be directed to patients younger than 50 years; no specific high-risk groups require special information.



Author Affiliations

From the Department of General Practice/Family Medicine, University of Utrecht, Utrecht, the Netherlands.



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Practice Commentary
Jogerst
Arch Fam Med 1997;6:163-163.
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