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The Routine Antenatal Diagnostic Imaging With Ultrasound StudyThe Challenge to Practice Evidence-Based Obstetrics
Louise Acheson, MD, MS;
Lisa Mitchell, PhD
Arch Fam Med. 1993;2(12):1229-1231.
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AFTER 6 YEARS of exemplary work, the Routine Antenatal Diagnostic Imaging With Ultrasound Study (RADIUS) has been published.1,2 This study is a randomized, controlled trial of routine screening ultrasound examinations at approximately 19 and 32 weeks' gestation for healthy, pregnant women who had no other indication for an ultrasound examination. This study was conducted in 109 obstetrical and family practices in the Midwest and New England. Sonograms were performed on state-of-the-art equipment using a comprehensive examination protocol and a thorough quality-control program. With 15 530 subjects randomized, this study, unlike previous ones, had the power to answer the question whether screening ultrasound examinations would affect perinatal mortality and morbidity. It did not address such outcomes as parent-infant interactions or physician and patient satisfaction.
The RADIUS trial represents a landmark for primary care research in the size and level of funding from the National Institutes of Health (Bethesda, Md), the
. . . [Full Text PDF of this Article]
Author Affiliations
Case Western Reserve University and University Hospitals of Cleveland Cleveland, Ohio; Montreal, Quebec
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