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Chronic Fatigue Syndromes: The Limbic Hypothesis
by Jay A. Goldstein, 259 pp, $89.95 hardcover, $49.95 softcover, ISBN 1-56024-433-X, New York, NY, The Haworth Medical Press, 1993.
Edmund S. Higgins, MD, MS, Reviewer
Medical University of South Carolina Charleston
Arch Fam Med. 1994;3(8):733-734.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings. |
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Since 1985, when the association between persistent fatigue and Epstein-Barr virus was first reported, there have been many reports documenting minor viral and immunologic abnormalities in patients with chronic fatigue syndrome (CFS). Unfortunately, no laboratory test has been found that can diagnose CFS and many have noted the close similarity between CFS and psychiatric disorders. In spite of this, some physicians have steadfastly maintained that CFS is a "real" medical condition.
In Chronic Fatigue Syndromes: The Limbic Hypothesis, Goldstein, a leader in the movement to prevent CFS from being defined as a psychiatric disorder, concludes that the brain is the locus of the disease. However, Goldstein maintains his biomedical perspective by proposing that the "limbic encephalopathy" is caused by a virus or some immune dysfunction. (Others have called his theory "hepatitis of the brain.") In a flurry of medical jargon, literature citations, and
. . . [Full Text PDF of this Article]
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