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Family-Centered Preventive Counseling for Coronary Heart Disease Risk FactorsIs It Time for a Randomized Clinical Trial?
Charles B. Eaton, MD
Arch Fam Med. 1997;6(4):361-362.
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MORE THAN 20 years ago, Sackett et al1 noted in the Framingham Heart Study that spouses had similar chollesterol levels, smoking habits, blood pressures, and weights. Researchers have speculated that these similarities in coronary heart disease (CHD) risk factor levels may be in part related to similarities in diet, physical activity patterns, body habitus, and other lifestyle issues held in common by spousal pairs. We also have known for the past 50 years that CHD aggregates in families2 and that a positive family history of CHD increases an individual's risk for CHD 2- to 10-fold depending on the age of the affected family member and the number of affected family members.3 We also know that family history of CHD is an independent risk factor for premature CHD even when accounting for nontraditional risk factors such as elevated levels of lipoprotein Lp(a), homocysteine, and fibrinogen as well
. . . [Full Text PDF of this Article]
Author Affiliations
Memorial Hospital of Rhode Island Pawtucket
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