A Commentary on “TGF-β1-Induced Expression of the Anti-Apoptotic PAI-1 Protein Requires EGFR Signaling”

Rolfe K.J; Grobbelaar A.O

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Cell Communication Insights

A Commentary on “TGF-β1-Induced Expression of the Anti-Apoptotic PAI-1 Protein Requires EGFR Signaling”

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Rolfe K.J and Grobbelaar A.O

Cell Communication Insights 2009:2 13-15

Short Commentary

Published on 07 Sep 2009

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Abstract

Plasminogen activator inhibitor-1 (PAI-1) has been found to affect a number of important cell processes and therefore abnormal expression of PAI-1 has been associated with a number of diseases and disorders. Understanding the transactivation of PAI-1 may result in identifying novel therapeutic targets.

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