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Clinical Medicine Reviews in Therapeutics

Intrasound Therapy is an Effective Adjunct in the Management of Osteoarthritis of the Knee: A Randomized Control Trial

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Clinical Medicine Reviews in Therapeutics 2015:7 11-17

Original Research

Published on 06 Dec 2015

DOI: 10.4137/CMRT.S30942


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Abstract

Intrasound therapy (IST) has been found to improve healing in acute injuries in animal models but no clinical study has been conducted on chronic degenerative conditions in human subjects. The purpose of this study was to investigate and compare the effects of IST and transcutaneous electrical nerve stimulation (TENS) in the management of knee osteoarthritis. Twenty-four patients were randomly assigned into three groups: IST, TENS, and the control group. Subjects in Group 1 had low-intensity IST for 10 minutes and closed-chain exercises, Group 2 subjects had TENS at a frequency of 100 Hz, a pulse width of 150 µs, continuous mode for 15 minutes and closed-chain exercises, while the control group patients had only closed-chain exercises. Treatment was given for eight weeks, twice weekly. Western Ontario and McMaster Universities Arthritis Index (WOMAC) scores, the distance covered in the 6-minute walk test, and knee range of motion were evaluated before and after the treatment. Data were analyzed using paired t-test and analysis of variance. Level of significance was set at P < 0.05. The clinical outcome measures improved significantly in the posttreatment of the three groups. Subjects in the three groups had significant differences in the mean change in the outcome variables for the WOMAC score (TENS = 29.13 ± 3.83; IST = 28.0 ± 1.72; and control = 13.71 ± 2.52). The post hoc analysis between IST and TENS showed no significant differences but IST had better clinical outcome than TENS. The results of this study suggest that IST may be an alternative to TENS as an adjunct therapy in the management of osteoarthritis of the knee.



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