Selective Inhibitors of Cyclooxygenase-2

  Figure 1.
Figure 1.

Prostanoid activities derived from COX activity. Prostaglandin G/H synthase (COX) is bifunctional: its bis-cyclooxygenase activity, directed both at C-11 and C-15 of arachidonic acid (AA), is indicated in purple; its hydroperoxidase activity, directed to the peroxide adduct at C-15 of prostaglandin G2 (PGG2), is indicated in blue.

This Article

  1. MI April 2001 vol. 1 no. 1 30-38