Inhibitors ofCapacitativeCalciumEntry
Inhibitor type | Examples | Ki (μM) |
---|---|---|
Cations | Lanthanides | 10 – 100 |
Gd3+ | ≤1 | |
Divalent cations | 1000-5000 | |
P-450 inhibitors | Econazole | 0.2-10 |
Miconazole | 0.5-1 | |
Clotrimazole | 2-20 | |
Ketoconazole | 15-80 | |
Cyclooxygenase inhibitors | Niflumic acid | 150 |
Flufenamic acid | 33 | |
Tenidap | 13.5 | |
Lipoxygenase inhibitors | Nordihydroguaiaretic acid | 12 |
Eicosatetraynoic acid | 4 | |
Channel blockers (putative) | SK&F 96365 | 3-48 |
SC38249 | 13 | |
LU52396 | 2 | |
L-651,582 | 1.2 | |
Tetrandrine | 20 | |
2-APB | 30 | |
Mechanism-based inhibitors | U73122 (phospholipase C inhibitor) | 10 |
Wortmannin (phosphatidylinositol kinase inhibitor) | 10 |