NOX Isoforms and Reactive Oxygen Species in Vascular Health
Figure 1
Regulation of NADPH oxidase (NOX) isoforms
NOX2 is the prototypical structure, showing the six transmembrane domains and cytosolic termini. Regulation of the four NOX isoforms that are relevant to cardiovascular health is mediated by variations of NOX isoform structure as well as interactions with various protein factors. See Table 1 and text for details.
