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Cytochromes P450, Drugs, and Diseases
Figure 2.
Major hepatic P450 enzymes involved in drug metabolism. Circles are intended to reflect the mean size of the pool of each of the main P450s (CYPs) in human liver (20–24). The exact pattern will vary among individuals. A few commonly recognized substrates, inhibitors, and inducers of these P450s are indicated. [ From an approach by Breimer. For extensive lists see Rendic (22).]
