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Serotonin 5-HT2 Receptors: Molecular and Genomic Diversity
Figure 2.
Functional consequences of RNA editing. RNA editing alters the G protein–coupling profile of the 5-HT2C receptor with subsequent fine-tuning of downstream signals. INI (Ile, Asn, Ile) and VGV (Val, Gly, Val) refer to the amino acid residues at position 156, 158, and 160 (see text for additional details). PLC, phospholipase C; PLD, phospolipase D.
