- Institution: Stanford Univ Med Ctr Lane Med Lib/Periodical Dept/Rm L109
- Sign In as Member / Individual
Transdermal Drug Delivery: PAST, PRESENT, FUTURE
Table 1.
Characteristics of Several Drugs Delivered Transdermally
| Active Ingredient | Mol. Wt. (Daltons) | Trade Name(s) | Daily Dose | Frequency of Application | Type of System |
|---|---|---|---|---|---|
| * Because these are OTC products, the manufacturer is not required to describe the formulation. | |||||
| Clonidine | 230 | Catapres-TTS® | 0.1–0.3 mg | Weekly | Reservoir |
| Estradiol | 272 | Esclim® | 0.025–0.1 mg | Weekly | Drug-in-adhesive |
| Vivelle® | |||||
| Vivelle-Dot® | |||||
| Climara® | |||||
| Ethinyl Estradiol | 296 | Ortho-Evra® | 0.15 mg | Weekly | Drug-in-adhesive |
| w/ Norelgestromin | 328 | 0.02 | |||
| Fentanyl | 337 | Duragesic | 0.6 mg | Once every three days | Reservoir |
| Transdermal System® | |||||
| Lidocaine | 234 | Lidoderm® | Not stated | Daily | Drug-in-adhesive |
| Nicotine | 162 | Nicoderm CQ® | 7–21 mg | Daily | * |
| Nicotrol® | |||||
| Nitroglycerine | 227 | Nitro-Dur® | 1.4–11.2 mg | Daily | Drug-in-adhesive |
| Nitrodisc® | Reservoir | ||||
| Scopolamine | 303 | Transderm-Scop® | 0.33 mg | Once every three days | Reservoir |
| Testosterone | 288 | Androderm® | 2.5–5 mg | Daily | Reservoir |
