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S-Glutathionylation: Indicator of Cell Stress and Regulator of the Unfolded Protein Response
Table 2:
S-glutathionylated proteins identified in human diseases.
| Protein | Diseasea | UPR activation |
|---|---|---|
| a Only those diseases in which S-glutathionylated proteins have been identified are shown. | ||
| b Numbers in parentheses indicate cited references. | ||
| Actin (85)b | Ischemia/Cardiovascular disease Friedreich’s ataxia | Yes (86) No |
| Tau (87) | Alzheimer’s disease | Yes (88) |
| Hemoglobin (89) | Type 2 diabetes | Yes (90) |
| CTFR (81) | Cystic fibrosis | Yes (91) |
| γ-S-crystallin (92) | Cataract disease | Yes (93) |
| Spectrin (57) | Sickle cell anemia | No |
