HETEROCYCLES
An International Journal for Reviews and Communications in Heterocyclic ChemistryWeb Edition ISSN: 1881-0942
Published online by The Japan Institute of Heterocyclic Chemistry
Special Issue
Special Issues of the 19th International Congress of Heterocyclic Chemistry's Special Issues, Vol. 21, No. 2, 1984
Published online:
■ New Synthesis of 1,4-Benzodiazepine Derivatives via Palladium Catalyzed Carbonylation
Miwako Mori, Minoru Ishikura, Masanao Terashima, Masaya Kimura, and Yoshio Ban
*Faculty of Pharmaceutical Sciences, Hokkaido University, Kita 12 Nishi 6, Kita-ku, Sapporo, Hokkaido 060-0812, Japan
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■ A Synthetic Approach to the Mechanism of DNA-Cleavage by Bleomycin-Fe(II)-O2 Complex
M. Otsuka, A. Kittaka, Y. Sugano, S. Kobayashi, Y. Sugiura, T. Takita, H. Umezawa, and M. Ohno
*Faculty of Pharmaceutical Sciences, University of Tokyo, Hongo, Bunkyo-ku, Tokyo 113, Japan
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■ Synthesis of β-Lactam Antibiotics via the Sulfeno-cycloamination
Masataka Ihara, Yo Haga, Mariko Yonekura, Keiichiro Fukumoto, and Tetsuji Kametani
*Graduate School of Pharmaceutical Sciences, Tohoku University, Aramaki, Aoba-ku, Sendai 980-8578, Japan
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■ 7α-Hydroxycephalosporin C, an Intermediate in the Methoxylation of Cephalosporin C by a Cell-Free Extract of S. Clavuligerus
J. D. Hood, A. Elson, M. L. Gilpin, and A. G. Brown
*Beecham Pharmaceuticals Research Division, Brockham Park, Betchworth, Surrey RH3 7AJ, U.K.
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■ Syntheses of Althiomycin and Its Analogs in Relation to Their Antibacterial Activities
Tetsuo Shiba, Kaoru Inami, and Hiromichi Imanaka
*Department of Chemistry, Faculty of Science, Osaka University, Toyonaka, Osaka 560-8531, Japan
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■ The Structure of Medermycin
Haruo Ogura and Kimio Furuhata
*School of Pharmaceutical Sciences, Kitasato University, 5-9-1, Shirokane, Minato-ku, Tokyo 108-8641, Japan
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■ Synthetic Study of Carbapenems Utilizing D-Glucosamine
N. Chida, M. Miyashita, and A. Yoshikoshi
*Chemical Research Institute of Non-Aqueous Solutions, Tohoku University, Katahira, Aoba-ku, Sendai 980-8577, Japan
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■ Asymmetric Synthesis of β-Lactams Using Chiral Five-membered Heterocyclic Compounds Derived from (+)-Tartaric Acid and L-Amino Acids
Nobuo Ikoto and Akira Hanaki
*National Institute of Radiological Sciences, 9-1, Anagawa-4-Chome, Inage-ku, Chiba 263-0024, Japan
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■ Asymmetric Synthesis of β-Lactam Antibiotics
A. Nishida, M. Shibasaki, and S. Ikegami
*Faculty of Pharmaceutical Sciences, Teikyo University, 1091-1 Suarashi, Sagamiko-machi, Tsukui-gun, Kanagawa 199-0195, Japan
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■ Synthesis and Antibacterial Activity of 2-Fluoroalkylthiopenems
Isao Kawamoto*, Rokuro Endo, Kosato Suzuki, and Shinichi Sugawara
*Chemical Research Laboratories and Analytical & Metabolic Research Laboratories, Sankyo Co., Ltd., 1-2-58 Hiromachi, Shinagawa-ku, Tokyo 140-8710, Japan
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■ Synthesis of Penem Antibiotics
A. K. Ganguly, A. Afonso, V. Girijavallabhan, and S. McCombie
*Organic Chemical Research Department, Schering-Plogh Research Institute, 60 Orange Street, Bloomfield, New Jersey 07003, U.S.A.
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■ Chemistry of 3-H-1-Carbacephem Compounds
T. Hirata, A. Sato, and S Kobayashi
*Pharmaceutical Research Institute, Kyowa Hakko Kogyo Co., Ltd.,, 1-6-1 Otemachi, Chiyoda, Tokyo 100-8185. Japan
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■ Synthesis of Penem and Cephem Antibiotics Employing Carbene Reaction
Tetsuji Kametani, Naoaki Kanaya, and Toshio Honda
*Faculty of Pharmaceutical Sciences, Hoshi University, 2-4-41 Ebara, Shinagawa-ku, Tokyo 142-8501, Japan
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■ Penicillin-Cephalosporin Conversion with Compleate Utilization of All the Framework Elements
Shigeru Torii, Hideo Tanaka,* Takashi Shiroi, and Michiko Sasaoka
*Department of Applied Chemistry, Faculty of Engineering, Okayama University, 3-1-1 Tsushima-naka, Okayama 700-8530, Japan
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■ A New Method for the Synthesis of 7α-Methoxycephalosporins
Kiyoaki Katano, Kunio Atsumi, Ken Nishihata, Fumio Kai, Eiichi Akita, Shigeharu Inoue, and Taro Niida
*Pharmaceutical Research Center, Meiji Seika Kaisha Ltd., 760 Morooka-cho, Kohoku-ku, Yokohama 222-8567, Japan
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■ A Simple Enantioselective Synthesis of β-Lactams
C. Hubschwerlen and G. Schmid
*Pharma Division, Pharma Preclinical Research & Development, F.Hoffmann-La Roche Ltd., Grenzacherstrasse 124, CH-4070 Basel, Switzerland
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■ Enantioselective Synthesis of Asparenomycin C by Chemicoenzymatic Approach
Susumu Kobayashi, Kazuo Okano, and Masaji Ohno
*Faculty of Pharmaceutical Sciences, University of Tokyo, Hongo, Bunkyo-ku, Tokyo 113, Japan
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■ Enantioselective Synthesis of Optically Active β-Lactams from D-Glyceraldehyde Acetonide
Hiroshi Matsunaga, Tomoko Sakamaki, Hiroto Nagaoka, and Yasuji Yamada
*Tokyo University of Pharmacy and Life Science, 1432-1 Horinouchi, Hachioji, Tokyo 192-0392, Japan
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■ The Chlorinolysis of Sulfer Containing β-Lactams
R. G. Micetich,* R. B. Morin, C. C. Shaw, and R. Singh
*Faculty of Pharmacy , University of Alberta, Edmonton, Alberta T6G, 2N8, Canada
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■ Synthesis of β-Lactams with Thienamycin-type Sidechain
Makoto Sunagawa, Koshiro Goda, Masao Enomoto, and Akira Sasaki
*Sumitomo Chemical Co. Ltd., 5-1 Soukai-cho, Niihama, Ehime 792-8521, Japan
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■ Synthesis of Thienamycin and 2-Alkylthiomethyl-carbapenam (2-Homo-thienamycin) Analogues from 6-Aminopenicillanic Acid
Tetsuo Hiraoka, Takeo Kobayashi, Noboru Ishida, Masao Shiozaki, Koichi Hirai, Hiroshi Maruyama, Sadao Sato, Chihiro Tamura, and Shinichi Sugawara
*Medicinal Chemistry Research Laboratories, Sankyo Co., Ltd., 1-2-58 Hiromachi, Shinagawa-ku, Tokyo 140-8710, Japan
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■ A Chiral Synthesis of Carbapenem Antibiotics from Penicillins
Matsuhiko Aratani, Kozo Sawada, Hideo Hirai, and Masashi Hashimoto
*Central research Laboratories, Fujisawa Pharmaceutical Co. Ltd., 2-1-6 Kashima, Yodogawa-ku, osaka 532, Japan
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■ Condensed Pyrazoles. Synthesis of Pyrazolo[3,4-d]pyrimidin-4-ones and Pyrazolo[3,4-b]quinolin-4-amines
Erik B. Pedersen, Søren V. Nielsen, and Peter Finlander
*Department of Chemistry, Odense University, Campusvej 55 DK-5230 Odense M., Denmark
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■ A Synthetic Method for Pyrrolo[1,4]benzodiazepine Antitumor Antibiotics
T. Kaneko,* H. Wong, and T. W. Doyle
*Pharmaceutical Reearch and Development, Bristol-Myers Company, P. O. Box 5100, Wallingford, CT 06492-5100, U.S.A.
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■ 1,3-Dienamines Reacting as 1,5-Dipoles in the Synthesis of N-Heterocycles
D. N. Reinhoudt, G. W. Visser, and W. Verboom
*Laboratory of Organic Chemistry, Twente University of Technology, Enschede, The Netherlands
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■ Antitumor Activity of Acodazole and Related Anilinoimidazo[4,5-f]quinolines
Frank F. Ebetino
*Norwivh Eaton Pharmaceuticals, Inc., Norwich, New York 13815, U.S.A.
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■ Interaction of 2-Aminodipyrido[1,2-a:3’,2’-d]imidazole with DNA. I. Structure of the Modified Nucleic Acid Base and Initial Chemical Event Caused by the Mutagen
Yuichi Hashimoto, Koichi Shudo, and Toshihiko Okamoto
*Institute of Molecular and Cellular Biosciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-0032, Japan
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■ Interaction of 2-Aminodipyrido[1,2-a:3’,2’-d]imidazole with DNA. II. Synthesis of New Intercalative Analogs
Ching-Shing Lee, Toshiharu Ohta, Yuichi Hashimoto, Koichi Shudo, and Toshihiko Okamoto
*Institute of Molecular and Cellular Biosciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-0032, Japan
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■ Bond Alternation and Mutagenicity of Azulenoquinolines and Diazulenopyridines
Tadayoshi Morita, Yoshiharu Takizawa, Shigeru Okita, Kahei Takase, Akio Tajiri, Keiji Wakabayashi, and Takashi Sugimura
*Graduate School of Science, Tohoku University, Aramaki, Aoba-ku, sendai 980-8578, Japan
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■ Synthesis of Potential Anti-Cancer Agents
N. N. Singh,* B. Singh, G. P. Singh, P. N. Singh, and P. U. Patna
*Panta University, Patna-800005, India