HETEROCYCLES
An International Journal for Reviews and Communications in Heterocyclic ChemistryWeb Edition ISSN: 1881-0942
Published online by The Japan Institute of Heterocyclic Chemistry
Regular Issue
Vol. 26, No. 7, 1987
Review | Regular issue | Vol 26, No. 7, 1987, pp.1947-1963
Published online:
■ Protoporphyrin-IX: Some Useful Substituent Manipulations
Published online:
DOI: 10.3987/R-1987-07-1947
■ Protoporphyrin-IX: Some Useful Substituent Manipulations
Kevin M. Smith and José A. S. Cavaleiro
*Department of Chemistry, University of California, One Shields Avenue, Davis, CA 95616-5295, U.S.A.
Abstract
Various substituent manipulations of the side chains in commercially available hemin (3) and its metal-free derivative, protoporphyrin-lX (4), are described, which illustrate the usefulness of these starting materials for preparation of a large number of theoretically, chemically, biologically, and spectroscopically useful porphyrins and hemes.