HETEROCYCLES
An International Journal for Reviews and Communications in Heterocyclic ChemistryWeb Edition ISSN: 1881-0942
Published online by The Japan Institute of Heterocyclic Chemistry
Special Issue
Shun-ichi Yamada's Special Issues, Vol. 46, No. 1, 1997
Published online:
■ Structures and Biogenesis of Manzamines and Related Alkaloids
Masashi Tsuda and Jun'ichi Kobayashi*
*Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo 060-0812, Japan
Abstract
Seven new manzamine-related alkaloids have been isolated together with known manzamine alkaloids from the Okinawan marine sponges of the genera Ircinia and Amphimedon. These alkaloids seem to be biogenetically related to manzamines A ~ C. We propose a plausible biogenetic path of manzamines A ~ C on the basis of the structures and ratios of all the manzaminerelated alkaloids isolated from the Amphimedon sponge. The structures and biogenesis of other manzamine-related alkaloids from marine sponges are also described.
Published online:
■ Heterocyclic Compounds Found in Bryophytes
Yoshinori Asakawa*
*Faculty of Pharmaceutical Sciences, Tokushima Bunri University, 180 Nishihamabouji, Yamashiro-machi, Tokushima, 770-8514, Japan
Abstract
Bryophytes contain various heterocyclic terpenoids and aromatic compounds which show occasionally interesting biological activity and are of very valuable for the chemosystematic study of bryophytes. The distribution of the heterocyclic compounds in the bryophytes and some biological activity of heterocyclic terpenoids and aromatic compounds isolated from the bryophytes will be reviewed.