Figure 3: Qa-1-CD94/NKG2A dependent suppression of delayed type hypersensitivity (DTH) response in anterior chamber associated immune deviation (ACAID) model in mice. ACAID associated suppression of antigen specific DTH is observed in CD94/NKG2A expressing mouse strain, but not in CD94/NKG2A deficient DBA/2J mice. ^[79] (a) Schematic representation of ACAID model, which illustrate ACAID mediated suppression of antigen mediated DTH in mice. (b) Suggested role of CD94/NKG2A-Qa-1 system for CD8 ⁺ immunosuppressive Tregs in ACAID ^[79] , where transforming growth factor beta may influence the generation of CD8 ⁺ Tregs ^{[104],[105],[106],[107]}