Serotonin 5-HT₂ Receptors: Molecular and Genomic Diversity

5-HT_2C R editing sites. Nucleotide sequence and predicted amino acid sequence alignments between the 5-HT_2CR genomic DNA and mRNA sequences. A-I changes are shown in boxes (red), site of editing unique to human 5-HT_2CR (blue box). The top row of amino acids indicates the predicted unedited residues, whereas the bottom row shows changes resulting from editing (underlined). The schematic diagram showcases the positions of the Cys23Ser SNP (yellow star) and editing sites (red circles) in the 5-HT_2CR.