Chemoprevention Goes Gourmet: Different Flavors of NO-Aspirin

The chemical structures of NO-aspirin and its positional isomers. The NO-aspirin molecule is made of aspirin (acetylsalicylic acid) covalently linked through an aromatic spacer to an NO-releasing moiety (–ONO₂). The three positional isomers of NO-aspirin, ortho, meta, and para, reflect the position of –ONO₂ group linkage on the aromatic spacer.