BEYOND AMYLOID: The Next Generation of Alzheimer’s Disease Therapeutics

A picture of the future: the Alzheimer’s disease healthcare cycle. This schematic highlights the importance of taking an integrated approach to identification of novel therapeutic targets for Alzheimer’s disease by considering not just the genetic basis of a given target but also its biological context and how biomarkers coupled to clinical endpoints will be needed to measure efficacy to establish medical value to patients and caregivers.