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The Obesity Epidemic: Pharmacological Challenges
Figure 4.
Effect of rimonabant on body weight (RIO-North America trial). In the second year of the trial, subjects who had been on the 20-mg daily dose were randomly re-assigned to either continue treatment or switch to placebo. The observed weight loss was also reflected in reduction of waist circumference (data not shown). [Data reproduced from (7). See text for details.]
