Home Print this page Email this page  Users Online: 53
Home About us Editorial board Search Ahead of print Current issue Archives Submit article Instructions Subscribe Contacts Login 
Year : 2014  |  Volume : 2  |  Issue : 2  |  Page : 62-64

Central nervous system toxoplasmosis in human immunodeficiency virus infection: Imaging findings

Department of Radiology, College of Medicine, University College Hospital, University of Ibadan, Ibadan, Nigeria

Correspondence Address:
Adenike Temitayo Adeniji-Sofoluwe
Department of Radiology, College of Medicine, University College Hospital, University of Ibadan, Ibadan
Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/2321-9157.159972

Rights and Permissions

Toxoplasmosis is one of the most common zoonoses worldwide caused by Toxoplasma gondii. Majority of T. gondii infections are asymptomatic or induce transitory and mild symptoms characterized by lymphadenopathy. Risk factors are immunosuppression and pregnancy. Human immunodeficiency virus (HIV) infected persons represent the group at highest risk of developing symptomatic toxoplasmosis especially with a CD4 count of <100, which can be fatal. A middle-aged acute-on-chronic ill-looking, conscious, lethargic but confused, pale man with lymphadenopathy involving the cervical, sub-mental and axillary nodes, and widespread fungal infections is presented. Neurologic imaging is frequently used in the diagnosis of central nervous system (CNS) toxoplasmosis in combination with serology and clinical assessment. Computed tomography scans show multiple, bilateral, contrast-enhancing ("ring enhancing"), focal brain lesions in 70-80% of patients with CNS toxoplasmosis. The course of disease can frequently be fatal if not recognized and treated early as was the case in this patient.

Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded129    
    Comments [Add]    
    Cited by others 1    

Recommend this journal